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[Assessment of the antiviral activity of 2HCl*H-His-Rim compound compared to the anti-influenza drug Arbidol for influenza caused by A/duck/Novosibirsk/56/05 (H5N1) (Influenza A virus, Alphainfluenzavirus, Orthomyxoviridae).]

Petr G DeriabinTimur Mansurovich GaraevMarina Pavlovna FinogenovaArtyom Irorevich Odnovorov
Published in: Voprosy virusologii (2021)
The 2HCl*H-His-Rim compound can be recommended as a candidate for preclinical and clinical trials in order to obtain an etiotropic antiviral drug based on it, due to its high efficacy and economic and synthetic availability. The synthetic compound 2HCl*H-His-Rim acts on influenza A virus variants resistant to Rimantadine and Amantadine.
Keyphrases
  • clinical trial
  • copy number
  • mesenchymal stem cells
  • dna methylation
  • bone marrow
  • study protocol
  • life cycle