Cardiac regeneration: All work and no repair?

Published in: Science translational medicine (2017)

Structural changes in the developing heart may influence the limited regenerative capacity of the adult heart. We examine how the workload exerted on the adult mammalian heart may limit regenerative capability and discuss recent therapies that demonstrate beneficial effects through unloading the heart.

Keyphrases

stem cells
heart failure
mesenchymal stem cells
atrial fibrillation
cell therapy
left ventricular
young adults
wound healing