A High-Cholesterol Diet Increases Toll-like Receptors and Other Harmful Factors in the Rabbit Myocardium: The Beneficial Effect of Statins.

Alkistis KapelouzouMichalis KatsimpoulasChristos KontogiannisIrene LidorikiGeorgios GeorgiopoulosChristos KourekChristos PapageorgiouKonstantinos S MylonasSpyridon DritsasAlexandros CharalabopoulosDennis V Cokkinos

Published in: Current issues in molecular biology (2021)

HCD increases the levels of TLRs; inflammatory, fibrotic and apoptotic factors; and BNP in the rabbit myocardium. Atherogenic diets adversely affect the myocardium at a molecular level and are reversed by statins.

Keyphrases

cardiovascular disease
weight loss
cell death
physical activity
systemic sclerosis
idiopathic pulmonary fibrosis
type diabetes
anti inflammatory