Carbon isotope ratio of endogenous urinary steroids of the Cuban population of athletes studied for doping purposes.
Rodny Montes de Oca PortoMiguel Angel Fernández HormigaMargarita Teresa Correa VidalDayamin Martinez-BritoPublished in: Drug testing and analysis (2020)
The aim of this work was to validate the gas chromatography/combustion/isotope ratio mass spectrometry method in Havana Antidoping Laboratory and verify its implementation with a study of the Cuban population. The method was precise and accurate inside the linear working range; the limit of quantification and the uncertainty were compliant with TD2019IRMS. The study of the Cuban population showed no differences in δ13 C values between females and males. Only three values of Δδ13 C showed significant differences between sexes (PD-T, OHA-T, and 11-keto-Et-T). The values of δ13 C between -17.8‰ and -21.2‰ (upper and lower limits based on normal distribution) were consistent with other populations where C4 plant derivatives prevail in the diet.
Keyphrases
- gas chromatography
- mass spectrometry
- tandem mass spectrometry
- high resolution mass spectrometry
- liquid chromatography
- high resolution
- primary care
- healthcare
- physical activity
- gas chromatography mass spectrometry
- high performance liquid chromatography
- solid phase extraction
- particulate matter
- quality improvement
- heavy metals
- genetic diversity
- cell wall
- plant growth