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Alternative pediatric metabolic syndrome definitions impact prevalence estimates and socioeconomic gradients.

Alexander LepeMarlou L A de KroonAndrea F de WinterSijmen A Reijneveld
Published in: Pediatric research (2021)
Little is known about the impact of using different definitions of pediatric metabolic syndrome on study results. Our study showed that the choice of pediatric metabolic syndrome definition produces very different prevalence estimates. We also showed that the choice of definition influences the socioeconomic gradient. However, low socioeconomic status was consistently a risk factor for having pediatric metabolic syndrome. In conclusion, studies using different definitions of metabolic syndrome could be reasonably compared when investigating the association with socioeconomic status but not always validly when comparing prevalence studies.
Keyphrases
  • metabolic syndrome
  • insulin resistance
  • uric acid
  • risk factors
  • cardiovascular risk factors
  • cardiovascular disease
  • case control
  • young adults
  • childhood cancer