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The epithelial adherens junction component PLEKHA7 regulates ECM remodeling and cell behavior through miRNA-mediated regulation of MMP1 and LOX.

Amanda C DaulagalaMetin CetinJoyce Nair-MenonDouglas W JimenezMary Catherine BridgesAmy D BradshawÖzgür SahinAntonis Kourtidis
Published in: bioRxiv : the preprint server for biology (2024)
Epithelial cells instruct ECM remodeling to modulate their behavior, as a result of adherens junction and miRNA disruption.
Keyphrases
  • extracellular matrix
  • single cell
  • cell therapy
  • stem cells
  • cell migration
  • mesenchymal stem cells
  • bone marrow
  • low density lipoprotein