Alpha globin gene copy number and incident ischemic stroke risk among Black Americans.
A Parker RuhlNeal JeffriesYu YangSteven BrooksRakhi P NaikLydia H PeckerBryan T MottCheryl A WinklerNicole D ArmstrongNeil A ZakaiOrlando M GutierrezSuzanne JuddVirginia HowardGeorge HowardMarguerite R IrvinMary CushmanHans C AckermanPublished in: medRxiv : the preprint server for health sciences (2023)
gene deletions are protective. Together, these population studies suggest that the physiological roles of alpha globin may differ between the renal and cerebral vascular beds.