Integrin β3 in forebrain Emx1-expressing cells regulates repetitive self-grooming and sociability in mice.

Andrew J LopuchBrian D SwinehartEden L WidenerZ Logan HolleyKatherine M BlandChristopher J HandwerkCooper A BrettHollyn N CookAnna R KalinowskiHilda V RodriguezM Irene SongGeorge S Vidal

Published in: BMC neuroscience (2022)

Together, these findings strengthen the idea that Itgb3 has a specific role in shaping forebrain circuitry that is relevant to endophenotypes of autism spectrum disorder.

Keyphrases

autism spectrum disorder
induced apoptosis
cell cycle arrest
high frequency
attention deficit hyperactivity disorder
high fat diet induced
endoplasmic reticulum stress
oxidative stress
cell death
type diabetes
signaling pathway
skeletal muscle
cell migration
cell adhesion