Assessing regional intracortical myelination in schizophrenia spectrum and bipolar disorders using the optimized T1w/T2w-ratio.

Kjetil Nordbø Jørgensen Stener Nerland Nora Berz Slapø Linn B Norbom Lynn Mørch-Johnsen Laura Anne Wortinger Claudia Barth Dimitrios Andreou Ivan I Maximov Oliver Marcel Geier Ole Andreas Andreassen Erik G Jönsson Ingrid Agartz

Published in: Psychological medicine (2024)

While we found no evidence of reduced intracortical myelin in SCZ or BPD relative to CTR, different regional age trajectories in SCZ may suggest a promyelinating effect of antipsychotic medication.

Keyphrases

bipolar disorder
depressive symptoms
healthcare
white matter
emergency department
adverse drug
electronic health record