Histological and structural effects of biodegradable polydioxanone stents in the rabbit trachea.
Rocío Morante-ValverdeAlicia UsateguiMaría López DíazMontserrat GrauMa Carmen Luna-ParedesSalomé AlbiMarina Alonso-RiañoJosé L PablosJuan L Antón-Pacheco SánchezPublished in: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery (2022)
According to our data, successive PDO stenting caused mild inflammatory changes in the tracheal wall and no increase in the collagen matrix, and the cartilaginous support was not modified during a long follow-up period (up to 42 weeks). These findings suggest that they may be safe and show good biocompatibility in the long term.