Successful determination of imatinib re-administration dosage by therapeutic drug monitoring in a case of chronic myeloid leukemia initiating dialysis for acute renal dysfunction.
Ryosuke NakaharaTakahiro SumimotoRyota TanakaMasao OgataHiroki ItohPublished in: Clinical case reports (2021)
Fixed dose regimen is currently the standard administration method for TKI. However, this case report indicated that TDM may by a useful approach to individualized dosing of TKI for the treatment of CML when initiating dialysis.
Keyphrases
- chronic myeloid leukemia
- case report
- chronic kidney disease
- end stage renal disease
- liver failure
- oxidative stress
- respiratory failure
- drug induced
- solid phase extraction
- intensive care unit
- molecularly imprinted
- combination therapy
- mass spectrometry
- high resolution
- replacement therapy
- acute respiratory distress syndrome