A Pan-respiratory Antiviral Chemotype Targeting a Transient Host Multiprotein Complex.
Andreas Müller-SchiffmannMaya MichonAnuradha F LingappaShao Feng YuLi DuFred DeiterSean BroceSuguna MalleshJackelyn CrabtreeUsha F LingappaAmanda MacieikLisa MüllerPhilipp Niklas OstermannMarcel AndréeOrtwin AdamsHeiner SchaalRobert J HoganRalph A TrippUmesh AppaiahSanjeev K AnandThomas W CampiMichael J FordJonathan C ReedJim LinOlayemi AkintundeKiel CopelandChristine NicholsEmma PetrouskiA Raquel MoreiraI-Ting JiangNicholas DeYarmanIan BrownSharon LauIlana SegalDanielle GoldsmithShi HongVinod AsundiErica M BriggsNgwe Sin PhyoMarkus FroehlichBruce OniskoKent MatlackDebendranath DeyJaisri R LingappaM Dharma PrasadAnatoliy KitaygorodskyyDennis SolasHomer BousheyJohn GreenlandSatish PillaiMichael K LoJoel M MontgomeryChristina F SpiropoulouCarsten KorthSuganya SelvarajahKumar PaulvannanVishwanath R LingappaPublished in: bioRxiv : the preprint server for biology (2022)
A host-targeted drug to treat all respiratory viruses without viral resistance development.