Conditional knockdown of OsMLH1 to improve plant prime editing systems without disturbing fertility in rice.

Xiaoshuang LiuDongfang GuYiru ZhangYingli JiangZhi XiaoRongfang XuRuiying QinJuan LiPengcheng Wei

Published in: Genome biology (2024)

This study provides a safe and reliable plant PE optimization strategy for improving editing efficiency without disturbing plant development via transient MMR inhibition with an excisable RNAi module of MLH1.

Keyphrases

crispr cas
cell wall
blood brain barrier