Carbon monoxide treatment reduces microglial activation in the ischemic rat retina.
Felix UlbrichUlrich GoebelDaniel BöhringerPetar CharalambousWolf Alexander LagrèzeJulia BiermannPublished in: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (2016)
Numerous activated microglia cells appear in the inner retina after I/R, and CO-treatment significantly attenuates this glial response. Antagonism of microglial activation may be a further neuroprotective effect of CO, apart from its direct anti-apoptotic capacity.