EpCAM-targeted betulinic acid analogue nanotherapy improves therapeutic efficacy and induces anti-tumorigenic immune response in colorectal cancer tumor microenvironment.
Debasmita DuttaAshique Al HoqueBrahamacharry PaulJun Hyoung ParkChinmay ChowdhuryMohiuddin QuadirSoumyabrata BanerjeeArghadip ChoudhurySoumik LahaNayim SepayPriyanka BoroBenny Abraham KaipparettuBiswajit MukherjeePublished in: Journal of biomedical science (2024)
Enhanced therapeutic efficacy and robust anti-tumorigenic immune response of Apt-2cNP in the CRC-TME are promising indicators of its potential as a prospective therapeutic agent for managing CRC. However, further studies are warranted.