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The PYK2 inhibitor PF-562271 enhances the effect of temozolomide on tumor growth in a C57Bl/6-Gl261 mouse glioma model.

Jescelica Ortiz-RiveraRebeca NuñezYuriy V KucheryavykhLilia Y Kucheryavykh
Published in: Journal of neuro-oncology (2023)
TMZ + PF-562271 eliminates TMZ-related Pyk2/FAK activation in GBM and improves the treatment efficacy.
Keyphrases
  • newly diagnosed
  • combination therapy
  • cell migration