Brain volume changes in spontaneous intracranial hypotension: Revisiting the Monro-Kellie doctrine.
Jr-Wei WuYen-Feng WangShu-Shya HseuShu-Ting ChenYung-Lin ChenYu-Te WuShih-Pin ChenJiing-Feng LirngShuu-Jiun WangPublished in: Cephalalgia : an international journal of headache (2020)
The current study found the brain tissue volume and ventricular cerebrospinal fluid are decreased in spontaneous intracranial hypotension patients. The change in ventricular cerebrospinal fluid volume, but not brain tissue volume change, was associated with the severity of spinal cerebrospinal fluid leakage. These results challenge the assumption that brain tissue volume is a fixed constant.
Keyphrases
- cerebrospinal fluid
- resting state
- white matter
- heart failure
- end stage renal disease
- functional connectivity
- left ventricular
- chronic kidney disease
- cerebral ischemia
- newly diagnosed
- spinal cord
- multiple sclerosis
- prognostic factors
- spinal cord injury
- brain injury
- patient reported outcomes
- optic nerve
- subarachnoid hemorrhage