Survival benefit associated with metformin use in inoperable non-small cell lung cancer patients with diabetes: A population-based retrospective cohort study.

Min-Chun ChuangYao-Hsu YangYing-Huang TsaiMeng-Jer HsiehYu-Ching LinChin-Kuo LinPau-Chung ChenTsung-Ming Yang

Published in: PloS one (2018)

Metformin use is associated with longer OS in inoperable NSCLC patients with diabetes, suggesting a potential anti-tumorigenic effect for metformin. Further research is needed to investigate the actual role of metformin in the treatment of NSCLC patients with diabetes.

Keyphrases

small cell lung cancer
advanced non small cell lung cancer
locally advanced
squamous cell carcinoma
radiation therapy
risk assessment
climate change
brain metastases
tyrosine kinase