The Influence of the Exclusion of Central Necrosis on [18F]FDG PET Radiomic Analysis.
Wyanne A NoortmanDennis VriensCharlotte D Y MooijCornelis H SlumpErik H J G AarntzenAnouk van BerkelHenri J L M TimmersJohan BussinkTineke W H MeijerLioe-Fee De Geus-OeiFloris H P van VeldenPublished in: Diagnostics (Basel, Switzerland) (2021)
In both tumour types, almost two-third of the features were affected, demonstrating that the impact of whether or not to include central necrosis in the VOI on the radiomic feature values is significant. Nevertheless, predictive performances of both delineation methods were comparable. We recommend that radiomic studies should report whether or not central necrosis was included during delineation.