Preparation of Zein-Based Nanoparticles: Nanoprecipitation versus Microfluidic-Assisted Manufacture, Effects of PEGylation on Nanoparticle Characteristics and Cellular Uptake by Melanoma Cells.

Jitkasem MeewanSukrut SomaniJamal Almowalad Partha LaskarMargaret MullinGraeme MacKenzieSwapnil KhadkeYvonne PerrieChristine Dufès

Published in: International journal of nanomedicine (2022)

mPEG5K-zein (0.5:1) nanoparticles prepared by nanoprecipitation were the most promising formulation in our study, exhibiting increased stability and enhancing coumarin-6 uptake by melanoma cancer cells.

Keyphrases

drug delivery
high throughput
single cell
circulating tumor cells
fluorescent probe