Inflammatory bowel disease induces inflammatory and pre-neoplastic changes in the prostate.

Anuj S DesaiVinay SagarBarbara LysyAdam B WeinerOliver S KoConor DriscollYara RodriguezRajita VatapalliKenji UnnoHuiying HanJason E CohenAmanda X VoMinh PhamMichael ShinKetan Jain-PosterJennifer RossElizabeth G MorencyTravis J MeyersJohn S WitteJennifer WuSarki A Abdulkadir Shilajit D Kundu

Published in: Prostate cancer and prostatic diseases (2021)

These data suggest chronic intestinal inflammation is associated with an inflammatory-rich, pro-tumorigenic prostatic phenotype which may explain how gut inflammation fosters prostate cancer development in men with IBD.

Keyphrases

prostate cancer
oxidative stress
radical prostatectomy
benign prostatic hyperplasia
electronic health record
anti inflammatory
machine learning
data analysis