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Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics.

Kelly StreetDavide RissoRussell B FletcherDiya DasJohn NgaiNir YosefElizabeth PurdomSandrine Dudoit
Published in: BMC genomics (2018)
Slingshot is a uniquely robust and flexible tool which combines the highly stable techniques necessary for noisy single-cell data with the ability to identify multiple trajectories. Accurate lineage inference is a critical step in the identification of dynamic temporal gene expression.
Keyphrases
  • single cell
  • gene expression
  • rna seq
  • high throughput
  • dna methylation
  • electronic health record
  • depressive symptoms
  • high resolution
  • stem cells
  • machine learning
  • bone marrow
  • solid state