Chromosome rearrangements shape the diversification of secondary metabolism in the cyclosporin producing fungus Tolypocladium inflatum.

Rodrigo A OlarteJon MenkeYing ZhangShawn SullivanJason C SlotYinyin HuangJonathan P BadalamentiAlisha C QuandtJoseph W SpataforaKathryn E Bushley

Published in: BMC genomics (2019)

This research places the evolution of SMBGCs within the context of whole genome evolution and suggests a role for recombination between chromosomes in generating novel SMBGCs in the medicinal fungus Tolypocladium inflatum.

Keyphrases

dna damage
dna repair
copy number
gene expression