Clinical applications of exercise in Parkinson's disease: what we need to know?
Sérgio MachadoDiogo Santos TeixeiraDiogo MonteiroClaudio ImperatoriEric Murillo-RodriguezFernanda Pereira da Silva RochaTetsuya YamamotoSandra Amatriain-FernándezHenning BuddeMauro Giovanni CartaLeonardo Ferreira CaixetaAlberto Souza de Sá FilhoPublished in: Expert review of neurotherapeutics (2022)
It is suggested that different intensities of aerobic exercise be explored for the treatment of PD. The results associated with high intensity seem promising for performance, physiological and clinical parameters, such as BDNF production and cognition. On the other hand, the diversification of tasks and repetition of motor gestures appear as consistent arguments to exercise prescription. Finally, for future investigations, the neuromodulation strategy in association with aerobic exercise appears as a potential inducer of benefits on gait and cognitive function.