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Macroprolactin over time: Is there any point in rechecking it in people with a persistently elevated serum prolactin?

Mark LivingstonSyeda F HashmiSudarshan RamachandranIan LaingAdrian H Heald
Published in: Clinical endocrinology (2024)
In this study, only 19/465 patients appeared to change macroprolactin status based on a 60% PEG recovery cut-off. The majority of these 19 patients were on antipsychotic/antidepressant medication(s) or had a prolactinoma; in only 7 did monomeric prolactin change significantly. This suggests that once macroprolactin status has been determined, clinical decision making is rarely affected by repeating it.
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