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Desmoplastic Melanoma of the Chest Wall: a Diagnostic Dilemma.

Adil Aziz KhanSufian ZaheerParth GulatiSana Ahuja
Published in: Indian journal of surgical oncology (2023)
Desmoplastic melanoma is an extremely rare subtype of malignant melanoma comprising only 1% of all the cutaneous melanomas. Being amelanotic and owing to its histopathological features of spindle cells lying in a collagenized stroma, it is often misdiagnosed as a dermatofibroma or scar tissue. The present case study describes a case of desmoplastic melanoma of the chest wall where the final diagnosis could be arrived at only after an extensive immunohistochemical panel to exclude other spindle cell proliferations.
Keyphrases
  • skin cancer
  • induced apoptosis
  • cell cycle arrest
  • single cell
  • cell therapy
  • basal cell carcinoma
  • oxidative stress
  • bone marrow
  • cell death
  • endoplasmic reticulum stress
  • cell proliferation
  • signaling pathway