Development of a drug delivering round window niche implant for cochlear pharmacotherapy.

Chunjiang WeiZiwen GaoMartina KnabelMartin UlbrichtStefan SenekowitschPeter ErfurtNorman MaggiBastian ZwickThomas EicknerFarnaz Matin-MannAnne SeidlitzThomas LenarzVerena Scheper

Published in: Drug delivery (2024)

We developed a GP-RNI that can be used for precise inner ear drug delivery in guinea pigs, providing a reliable platform for testing the RNI's safety and efficacy, with potential implications for future clinical translation.

Keyphrases

drug delivery
current status
high throughput
cancer therapy
soft tissue
hearing loss
human health
drug induced