Variation of Plasma Damage-Associated Molecular Patterns in Patients with Advanced Solid Tumors After Standard of Care Systemic Treatment.

Vicente ValentíLaia CapdevilaIsabel RuizFrancisco Javier Ramos PascualJoan BadiaSusana BlázquezÓscar VilluendasCristina PérezLaura Fernández-SenderMónica CórdobaCarlos Alonso-Villaverde

Published in: Cancer investigation (2023)

Signals of ICD were not observed. S100A8 behaves as an inflammatory marker with decreased concentration after treatment, mostly in RECIST-responders. PFS and OS were significantly prolonged in those patients who experienced a decrease of S100A8 compared with those patients who experienced increase of plasma S100A8 at three months.

Keyphrases

oxidative stress
healthcare
palliative care
quality improvement
pain management
combination therapy