Does Morphine Exposure Before Gestation Change Anxiety-Like Behavior During Morphine Dependence in Male Wistar Rats?

Saba Sabzevari Kiyana Rohbani Mahsa Sadeghi-Adl Solmaz Khalifeh Mitra-Sadat Sadat-Shirazi Mohammad-Reza Zarrindast

Published in: Addiction & health (2023)

The offspring of morphine-abstinent parents exhibited an anxious phenotype. Disruption of the HPA axis was seen in the progeny of maternal and biparental morphine-exposed rats. Indeed, morphine exposure for 21 days did not change anxiety-like behavior in these offspring which might be correlated to disruption of HPA axis in them.

Keyphrases

preterm infants
sleep quality
metabolic syndrome
pregnant women
birth weight
skeletal muscle
gestational age
pregnancy outcomes