Tetraspanin profiles of serum extracellular vesicles reflect functional limitations and pain perception in knee osteoarthritis.

Anne-Mari J MustonenMari PalviainenLaura SäisänenLauri KarttunenSylvain TollisAmir EsrafilianJusa ReijonenPetro JulkunenPia R-M SiljanderHeikki KrögerJussi MäkiJari ArokoskiPetteri Nieminen

Published in: Arthritis research & therapy (2024)

Particular serum EV subpopulations showed clear associations with KOA pain and functional limitations, suggesting that their implications in OA pathophysiology warrant further study.

Keyphrases

knee osteoarthritis
chronic pain
pain management
neuropathic pain
spinal cord injury
postoperative pain
spinal cord