Beneficial effects of δ-tocotrienol against oxidative stress in osteoblastic cells: studies on the mechanisms of action.
Lavinia CasatiFrancesca PaganiPatrizia LimontaClaudia VanettiGiovanni StancariValeria SibiliaPublished in: European journal of nutrition (2019)
The δ-TT protective effect against oxidative damage in MC3T3-E1 cells is due to a reduction of intracellular ROS levels and an increase of the GSH/GSSG ratio, and involves an interaction between the PI3K/Akt-Nrf2 signaling pathways.