Microbial hydrogen "manufactory" for enhanced gas therapy and self-activated immunotherapy via reduced immune escape.
Hongyu YanMiao FanHuifang LiuTingshan XiaoDandan HanRuijun CheWei ZhangXiaohan ZhouJune WangChi ZhangXinjian YangJinchao ZhangZhenhua LiPublished in: Journal of nanobiotechnology (2022)
Hydrogen-immunotherapy significantly kills tumor cells. We believe that our live microbial hydrogen production system provides a new strategy for cancer hydrogen treatment combining with enhanced immunotherapy without up-regulating PD-L1.