Activity-based anorexia disrupts systemic oxidative state and induces cortical mitochondrial fission in adolescent female rats.
Matthew M HurleyKateryna MurlanovaLindsey K MaciasAliasgher I SabirShannon C O'BrienHarshit BhasinKellie L TamashiroMikhail V PletnikovTimothy H MoranPublished in: The International journal of eating disorders (2020)
These data suggest that ABA experience results in oxidative stress that is remedied after weight restoration. The long-lasting ramifications of transient periods of increased oxidative stress are unknown and can lead to significant consequences on brain function and behavior.
Keyphrases
- oxidative stress
- diabetic rats
- dna damage
- induced apoptosis
- ischemia reperfusion injury
- young adults
- cerebral ischemia
- mental health
- transcription factor
- white matter
- body mass index
- physical activity
- weight loss
- weight gain
- multiple sclerosis
- arabidopsis thaliana
- brain injury
- blood brain barrier
- endoplasmic reticulum stress
- deep learning
- childhood cancer