Login / Signup

Possible genetical predictors of efficacy and safety of budesonide-MMX in patients with mild-to-moderate ulcerative colitis, and safety comparison with methylprednisolone.

Tamás ResálKatalin MangóPéter BacsurKata Judit SzántóDaniella PigniczkiCsilla KeresztesMariann RutkaAnita BálintÁgnes MilassinRenáta BorAnna FábiánZoltán SzepesKlaudia FarkasKatalin MonostoryTamás Molnár
Published in: Expert opinion on drug safety (2023)
CYP genotypes can affect the efficacy of budesonide-MMX; however, further studies would be needed with analyses of gene expression. Although budesonide-MMX is safer than methylprednisolone, due to glucocorticoid-related side effects, admission should require greater precaution.
Keyphrases
  • gene expression
  • ulcerative colitis
  • high dose
  • dna methylation
  • low dose
  • drug induced