Adrenomedullin ameliorates palmitic acid-induced insulin resistance through PI3K/Akt pathway in adipocytes.

Hang-Bing DaiHong-Yu WangFang-Zheng WangPei QianQing GaoHong ZhouYe-Bo Zhou

Published in: Acta diabetologica (2022)

This study demonstrates a prevention potential of ADM against obesity-related metabolic disorders, due to its protective effects against IR, inflammation and oxidative stress in adipocytes.

Keyphrases

insulin resistance
oxidative stress
high fat diet induced
adipose tissue
metabolic syndrome
type diabetes
high fat diet
skeletal muscle
polycystic ovary syndrome
ischemia reperfusion injury
dna damage
weight loss
diabetic rats
weight gain
human health
physical activity
glycemic control
endoplasmic reticulum stress