Hepatic and splenic 18 F-FDG blood clearance rates (Ki) in hepatic steatosis and diabetes mellitus.

Georgia KeramidaLuisa Roldao PereiraGuven KayaA Michael Peters

Published in: Clinical physiology and functional imaging (2019)

As BGL increases, hepatocyte glucokinase is up-regulated. This includes patients with HS and DM2 but not DM1. We speculate that in HS and DM2, up-regulation results from insulin resistance and hyperinsulinaemia. The data also support a hepato-splenic metabolic axis.

Keyphrases

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