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Genome-wide analysis of DNA replication timing in single cells: Yes! We're all individuals.

Anne D DonaldsonConrad A Nieduszynski
Published in: Genome biology (2019)
Recent studies have accomplished the extraordinary feat of measuring the exact status of DNA replication in individual cells. We outline how these studies have revealed surprising uniformity in how cells replicate their DNA, and consider the implications of this remarkable technological advance.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • endoplasmic reticulum stress
  • cell death
  • genome wide analysis
  • cell proliferation
  • pi k akt
  • density functional theory
  • single molecule