LPS-Treated Podocytes Polarize Naive CD4+ T Cells into Th17 and Treg Cells.
Da-Hai YuanYang JiaOmar Mohamud HassanLi-Yun XuXiao-Chuan WuPublished in: BioMed research international (2020)
Our study proved that CD80 and MHC II were constitutively expressed in podocytes but not upregulated by LPS. LPS-treated podocytes could polarize naive CD4+ T cells into Th17 and Treg cells and affect the Th17/Treg balance and may incline to cause a Th17 response.