Fetoplacental unit involvement in uric acid production in women with severe preeclampsia: a prospective case control pilot study.
Simon ShenhavIris HarelIdo SoltAmit ShenhavShlomo FytlovichDorit AharoniAvi RimlerEyal Y AntebyYaniv S OvadiaPublished in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (2024)
Despite preserved renal functions, UA and XO levels were elevated in women with PE. Importantly, this pattern was found to be applied to the feto-placental unit as well, which may indicate an active involvement of the fetus in the hypoxic process. Further study is needed to clarify the possible role of the feto-placental unit in pregnancies complicated by PE.