Preparation of rutin-loaded mesoporous silica nanoparticles and evaluation of its physicochemical, anticancer, and antibacterial properties.

Mohammad Yousef MemarElaheh Dalir AbdolahiniaMina YekaniMaryam KouhsoltaniSimin SharifiSolmaz Maleki Dizaj

Published in: Molecular biology reports (2022)

The anticancer and antibacterial effects of RUT-MSNs were considerably more than rutin. RUT-MSNs inhibited the growth of HN5 cells by inducing apoptosis and producing ROS. These results suggest that RUT-MSNs may be useful in the treatment of cancers and infections.

Keyphrases

cell cycle arrest
cell death
induced apoptosis
endoplasmic reticulum stress
oxidative stress
silver nanoparticles
wound healing
drug delivery
dna damage
anti inflammatory
cancer therapy
essential oil
signaling pathway
molecularly imprinted
high resolution