TNF-α, IL-1B and IL-6 affect the differentiation ability of dental pulp stem cells.
Sema Sonmez KaplanHesna Sazak OvecogluDeniz GencTunc AkkocPublished in: BMC oral health (2023)
DPSCs have high osteogenic, chondrogenic, and adipogenic differentiation capabilities. Pretreatment with inflammatory cytokines decreases the differentiation ability in vitro, thus inhibiting tissue formation.