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Spectroscopic imaging of D-2-hydroxyglutarate and other metabolites in pre-surgical patients with IDH-mutant lower-grade gliomas.

Adam W AutryMarisa LafontaineLlewellyn JalbertElizabeth PhillipsJoanna J PhillipsJavier Villanueva-MeyerMitchel S BergerSusan M ChangYan Li
Published in: Journal of neuro-oncology (2022)
In vivo 2HG detection can reasonably be achieved on clinical scanners and increased levels may signal adverse PFS.
Keyphrases
  • wild type
  • high grade
  • high resolution
  • molecular docking
  • low grade
  • ms ms
  • loop mediated isothermal amplification
  • label free
  • fluorescent probe
  • emergency department
  • living cells
  • sensitive detection
  • drug induced