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Diabetic ketoacidosis in children newly diagnosed with type 1 diabetes mellitus: Role of demographic, clinical, and biochemical features along with genetic and immunological markers as risk factors. A 20-year experience in a tertiary Belgian center.

Alfredo VicinanzaAnissa MessaaouiSylvie TenoutasseHarry Dorchy
Published in: Pediatric diabetes (2019)
This was the first reported implication of IA-2A positivity and neutral genotypes predisposing to DKA at diagnosis regardless of its severity. Earlier diagnosis through genetic and immunological screening of high-risk children could decrease DKA incidence at diabetes onset.
Keyphrases
  • risk factors
  • newly diagnosed
  • type diabetes
  • young adults
  • genome wide
  • cardiovascular disease
  • copy number
  • gene expression
  • glycemic control
  • wound healing
  • insulin resistance