Finite Mixtures of Latent Trait Analyzers With Concomitant Variables for Bipartite Networks: An Analysis of COVID-19 Data.
Dalila FailliMaria Francesca MarinoFrancesca MartellaPublished in: Multivariate behavioral research (2024)
Networks consist of interconnected units, known as nodes, and allow to formally describe interactions within a system. Specifically, bipartite networks depict relationships between two distinct sets of nodes, designated as sending and receiving nodes. An integral aspect of bipartite network analysis often involves identifying clusters of nodes with similar behaviors. The computational complexity of models for large bipartite networks poses a challenge. To mitigate this challenge, we employ a Mixture of Latent Trait Analyzers (MLTA) for node clustering. Our approach extends the MLTA to include covariates and introduces a double EM algorithm for estimation. Applying our method to COVID-19 data, with sending nodes representing patients and receiving nodes representing preventive measures, enables dimensionality reduction and the identification of meaningful groups. We present simulation results demonstrating the accuracy of the proposed method.
Keyphrases
- sentinel lymph node
- coronavirus disease
- network analysis
- lymph node
- sars cov
- end stage renal disease
- neoadjuvant chemotherapy
- electronic health record
- chronic kidney disease
- machine learning
- newly diagnosed
- ejection fraction
- big data
- squamous cell carcinoma
- deep learning
- single cell
- dna methylation
- ionic liquid
- gene expression
- patient reported outcomes
- rna seq
- artificial intelligence