Microtubules provide guidance cues for myofibril and sarcomere assembly and growth.
Nagaraju DhanyasiK VijayRaghavanBen-Zion ShiloEyal D SchejterPublished in: Developmental dynamics : an official publication of the American Association of Anatomists (2020)
Our observations highlight a surprisingly significant, behind-the-scenes role for microtubules in establishment of myofibril and sarcomere spatial patterns and size, and provide a detailed account of the interplay between major cytoskeletal elements in generating these essential contractile myogenic units.
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