Disulfiram-Loaded Niosomes Reduces Cancerous Phenotypes in Oral Squamous Cell Carcinoma Cells.

Melika Zangeneh MotlaghNazanin MahdaviZohreh Miri-LavasaniPouyan AminishakibMahsa KhoramipourMandana Kazem ArkiZohreh MirlavasniNiloufar RezaeiNikoo Hossein-Khannazer Abdolhossein Shahverdi

Published in: Cell journal (2023)

Our findings indicated that the application of proper dose of DSF-loaded Niosomes (12.5 μg/ml) increases apoptosis, decreases colony formation capacity and declines the migration ability of OSCC cells.

Keyphrases

cell cycle arrest
squamous cell
drug delivery
induced apoptosis
cell death
endoplasmic reticulum stress
cancer therapy
pi k akt
oxidative stress
wound healing
cell proliferation