Optimization of compound-specific chlorine stable isotope analysis of chloroform using the Taguchi design of experiments.
Berhane Abrha AsfawKaori Sakaguchi-SöderAnat BernsteinHagar SiebnerChristoph SchüthPublished in: Rapid communications in mass spectrometry : RCM (2020)
A simple online method for Cl-CSIA of chloroform was optimized with the Taguchi design of experiments. The Taguchi method was very useful for the optimization of the analytical conditions. However, the purging conditions should be fine-tuned and selected so that sufficient extraction of a target compound is confirmed to acquire a stable and higher precision of the method.