Mild behavioral impairment domains are longitudinally associated with pTAU and metabolic biomarkers in dementia-free older adults.

Emmanuel González-BautistaMarie MomméjaAdelaïde de MauléonZahinoor IsmailBruno VellasJulien DelrieuMaria E Soto Martin

Published in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2024)

Mild behavioral impairment (MBI) psychosis was associated with steeper increases in plasma p. pTau could be a pharmacological target to treat agitation and psychosis symptoms. MBI domains were linked to metabolic dysregulation involving insulin and homocysteine.

Keyphrases

type diabetes
mild cognitive impairment
cognitive impairment
glycemic control
metabolic syndrome
adipose tissue
depressive symptoms
skeletal muscle
sleep quality