Neurocognitive impairment and patient-proxy agreement on health-related quality of life evaluations in recurrent high-grade glioma patients.
Ivan CaramannaMartin KleinMartin van den BentAhmed IdbaihWolfgang WickMartin J B TaphoornLinda DirvenAndrew BottomleyJaap C Reijneveldnull nullPublished in: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation (2022)
While patient-proxy agreement on health-related quality of life outcomes is somewhat higher in cognitively intact patients, agreement in high-grade glioma patients is low in general. In light of these findings, we suggest to cautiously consider the use of proxy's evaluation in lieu of patient-reported outcomes, regardless of patient's neurocognitive status.