Risk of severe clinical events after sustained virological response following direct-acting antiviral therapy in HIV and hepatitis C virus coinfected participants.
Mathieu ChalouniLinda WittkopFirouzé Bani-SadrKarine LacombeLaure EsterleCamille GilbertPatrick MiailhesDavid ZucmanMarc Antoine ValantinSylvie Brégigeon-RonotPhilippe MorlatEric BillaudLionel PirothAlissa NaqviPhilippe SogniDominique Salmonnull nullPublished in: HIV medicine (2021)
After SVR following a DAA treatment, liver-related and AIDS-defining events were observed less frequently than NLNA cancers. Severity of liver disease was associated with the risk of liver-related events and of overall mortality but not with ischaemic events and NLNA cancers. Factors reflecting HIV infection were associated with NLNA cancers and liver-related events.